Quick-Neuron™ Excitatory - Human iPSC-derived Neurons Autism Spectrum Disorder - (M, 10yr, Caucasian, not Latino)

Cryopreserved human iPSC-derived excitatory neurons from Autism Spectrum Disorder patient (M, 10)
As low as ¥285,000.00
Our proprietary transcription factor-based stem cell differentiation method produces neurons without a genetic footprint. Quick-Neuron™ Excitatory - Human iPSC-derived Neurons display typical neurite outgrowth and express neuronal markers, such as TUBB3 (pan-neuronal) and vGLUT1 (glutamatergic). When thawed and maintained according to the instructions in the user guide, the iPSC-derived neurons are viable long-term and are suitable for a variety of characterization and neurotoxicity assays.
More Information
Short Description Cryopreserved human iPSC-derived excitatory neurons from Autism Spectrum Disorder patient (M, 10)
Product Components Cryopreserved cells, Component N, Component G2', and Component P
Starting Material iPSCs derived from peripheral blood mononuclear cells (CIRM line CW20026)
Product Use This product is for research use only. It is not approved for use in humans or for therapeutic or diagnostic use.
Storage Conditions Frozen cells should be stored in liquid (vapor phase). The rest of the components should be stored at -20°C.
Cell Type Excitatory Neurons
Culture Type Feeder Cell-Free
Disease Autism Spectrum Disorder
Donor Sex Male
Donor Race Ethnicity Caucasian, not Latino
Patient History See Resources section for more information.
Reprogramming Method Episomal vector
Induction Method Transcription factors delivered by Sendai virus
Growth Properties Adherent
Shipping Conditions Dry ice (domestic) or liquid nitrogen (international)
Shelf Life 1 year
Donor Age At Sampling 10
Donor data for CIRM line: CW20026




いいえ。当社の分化キットやiPS細胞由来分化細胞を使用するのに、追加ライセンスやMTA(Material Transfer Agreement)は必要ありません。ただし、これらの製品は研究用に限ります。 一方、mRNAのCDMOサービスについては個別の案件で異なりますので、問い合わせください。






Quick-Tissue™技術で使用されるセンダイウイルス(SeV)はRNAウイルスですので、ゲノムDNAに組み込まれることはありません。、原則として、RNAとして細胞に導入された外来遺伝子は、またmRNAで導入された場合でも、DNAと違い細胞核内に入り込む必要がなく、すぐさま翻訳され発現されます。よって、ゲノム上の遺伝子を変異させることはありません。これは以下の総説で論じられています。Yamamoto, et al. (2009) "Current prospects for mRNA gene delivery." Eur. Eur.J. Pharm Biopharm 71, 484-489.