Quick-Glia™ Astrocytes - Human iPSC-derived Astrocytes (F, 50 yr donor) - ALS (FUS mutant)

Cryopreserved human iPSC-derived astrocytes from Amyotrophic Lateral Sclerosis patient (F, 50)
AS-SeV-SK009
Our proprietary transcription factor-based stem cell differentiation method produces highly pure populations of astrocytes without a genetic footprint. Quick-Glia™ Astrocytes - Human iPSC-derived Astrocytes display typical astrocyte morphology and markers such as S100 Calcium Binding Protein β (S100β), Chondroitin Sulfate Proteoglycan 8 (CD44), Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1), and mature astrocyte marker Glial Fibrillary Acidic Protein (GFAP). When handled and maintained according to the instructions in this user guide, astrocytes are viable long-term and are suitable for a variety of characterization and neurotoxicity assays.
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Short Description Cryopreserved human iPSC-derived astrocytes from Amyotrophic Lateral Sclerosis patient (F, 50)
Product Components Cryopreserved cells, Component P
Starting Material iPSCs derived from fibroblasts derived from a skin punch biopsy (NINDS line NDS00132)
Product Use This product is for research use only. It is not approved for use in humans or for therapeutic or diagnostic use.
Storage Conditions Frozen cells should be stored in liquid (vapor phase). The rest of the components should be stored at -20°C.
Cell Type Astrocytes
Culture Type Feeder Cell-Free
Disease ALS
Donor Sex Female
Donor Race Ethnicity African-American
Disease Mutation FUS
Patient History See Resources section for more information.
Reprogramming Method mRNA transfection
Induction Method Transcription factors delivered by Sendai virus
Growth Properties Adherent
Shipping Conditions Dry ice (domestic) or liquid nitrogen (international)
Shelf Life 1 year
Donor Age At Sampling 50